A structural genomics approach to investigate Dystrophin mutations and their impact on the molecular pathways of Duchenne muscular dystrophy
This study provides novel insights into the molecular mechanisms of DMD, highlighting specific mutations that disrupt Dystrophin's solubility and function. These findings could inform future therapeutic strategies targeting Dystrophin mutations to address DMD pathogenesis.
Authors
- Anas Shamsi (ORCID: https://orcid.org/0000-0001-7055-7056)
- Farah Anjum (ORCID: https://orcid.org/0000-0002-8597-6015)
- Abdelbaset Mohamed Elasbali (ORCID: https://orcid.org/0000-0002-7003-9846)
- Mohd Adnan (ORCID: https://orcid.org/0000-0002-7080-6822)
- Md. Imtaiyaz Hassan (ORCID: https://orcid.org/0000-0002-3663-4940)
- Waleed Abu Al‐Soud (ORCID: https://orcid.org/0000-0002-1488-4826)
- Osama A. AlKhamees
Institutions
- Taif University (SA)
- Ajman University (AE)
- Jouf University (SA)
- Imam Mohammad ibn Saud Islamic University (SA)
- University of Ha'il (SA)
- Jamia Millia Islamia (IN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-02-04
- DOI
- https://doi.org/10.3389/fgene.2025.1517707
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Council of Scientific and Industrial Research, India
- Taif University
- Ajman University