Immune thrombocytopenia with retinopathy of prematurity

A growth-faltered preterm newborn weighing 1150 g was referred to our retinal unit for advanced retinopathy of prematurity.The infant had three interrelated ailments at presentation: Severe thrombocytopenia (<10,000/mm 3 ), rashes, and advanced fibroproliferative retinopathy of prematurity.The preterm newborn was admitted and investigated for the ailments.The infant was hemodynamically stable, antibiotics for late-onset sepsis were ongoing, and striking rashes limited to palms and soles were noted [Figure 1].Initial investigations for C-reactive protein, renal, and liver function tests were unremarkable.Blood/urine cultures for bacterial/fungal elements were negative.Titers for the congenital and perinatal infection etiology, including TORCHes, were non-reactive.Viral cultures were not available in our center.Maternal syphilis titers were non-reactive.Maternal antinuclear antibody was negative.The infant was managed for severe thrombocytopenia with serial platelet transfusions, optimized enteral nutrition, and retinal intervention of laser photocoagulation.The birth hospitalization of the male infant was for the vaginal premature birth at 28 weeks of gestation and 930 g, appropriate for gestation.He was cared for respiratory distress syndrome and possible sepsis.At 4-6 weeks of age, the newborn was detected for advanced retinopathy https://jlabphy.org/