A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021)

During the vaccination period, the risk of in-hospital mortality (IHM) was 29% lower than in the prevaccination period, after adjusting for sex, age, and comorbidities. This reduced risk was observed across sexes, age groups, and comorbidities. The risk factors for IHM remained consistent between the two periods, with age as the main risk factor, while female sex and dyslipidemia were identified as protective factors.

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Journal
Frontiers in Public Health
Published
2025-02-04
DOI
https://doi.org/10.3389/fpubh.2025.1488283
Primary Topic
COVID-19 and healthcare impacts
Type
article
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article

A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021)

Esperanza Merino, José Manuel Ramos, José Sánchez–Payá, Pilar González-de-la-Aleja et al.
Frontiers in Public Health
COVID-19 and healthcare impacts
article

A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021)

Esperanza Merino, José Manuel Ramos, José Sánchez–Payá, Pilar González-de-la-Aleja, Juan Carlos Rodrı́guez
article en

Abstract

During the vaccination period, the risk of in-hospital mortality (IHM) was 29% lower than in the prevaccination period, after adjusting for sex, age, and comorbidities. This reduced risk was observed across sexes, age groups, and comorbidities. The risk factors for IHM remained consistent between the two periods, with age as the main risk factor, while female sex and dyslipidemia were identified as protective factors.

Frontiers in Public HealthVol. 13
Universitat de Miguel Hernández d'Elx (ES), Hospital General Universitario de Alicante Doctor Balmis (ES)
Openalex Percentile: Top 97%
COVID-19 and healthcare impacts
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A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021) — Esperanza Merino, José Manuel Ramos, et al. · Frontiers in Public Health (2025) | TGRS Research Map | TGRS