Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity
Our findings strongly suggest that modulation of siglec-E pathways might have a protective effect at least in part against AT inflammation and metabolic disorders.
Authors
- Daniel M. Collier (ORCID: https://orcid.org/0000-0001-9431-9271)
- Lexiao Li (ORCID: https://orcid.org/0000-0002-3693-5452)
- Frank Park (ORCID: https://orcid.org/0000-0003-2324-2937)
- Jianxiong Jiang (ORCID: https://orcid.org/0000-0003-3955-8928)
- Sonia Kiran (ORCID: https://orcid.org/0000-0002-0193-4812)
- Ahmed Rakib (ORCID: https://orcid.org/0000-0003-3335-0368)
- Nelufar Yasmen
- Mousumi Mandal (ORCID: https://orcid.org/0000-0001-8131-1668)
- Udai P. Singh (ORCID: https://orcid.org/0000-0002-5910-5275)
- Md Abdullah Al Mamun (ORCID: https://orcid.org/0000-0002-0816-1808)
Institutions
- University of Tennessee Health Science Center (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-04
- DOI
- https://doi.org/10.3389/fimmu.2025.1501307
- Citations
- 3
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases
- National Institute of Neurological Disorders and Stroke