Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barrier in APP/PS1 mice
MA can significantly reduce intestinal inflammation and alleviate destruction of the intestinal mucosal barrier in APP/PS1 mice. SCFAs/FFAR3/NF-κB may be important targets through which MA benignly regulates intestinal mucosal barrier function.
Authors
- Xin Hao (ORCID: https://orcid.org/0000-0001-9559-884X)
- Yue Zhang (ORCID: https://orcid.org/0000-0002-6140-3757)
- Zhigang Li (ORCID: https://orcid.org/0000-0002-6224-1833)
- Ning Ding
- Yanxiang Zhang
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-02-04
- DOI
- https://doi.org/10.3389/fnins.2025.1509581
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- National Natural Science Foundation of China
- China Academy of Chinese Medical Sciences