Discovery and in vitro characterization of a human anti-CD36 scFv
We discovered a new fully human scFv that is an effective blocker of CD36. Since D11 reduces the acquisition of pathogenic features induced by CD36 ligands, it could support the generation of therapeutic proteins targeting CD36.
Authors
- Keyla Gómez-Castellano (ORCID: https://orcid.org/0000-0002-0903-0236)
- Marco A. Velasco‐Velázquez (ORCID: https://orcid.org/0000-0001-9717-0265)
- Sonia Mayra Pérez‐Tapia (ORCID: https://orcid.org/0000-0002-2818-8522)
- Cecilia Mata-Cruz
- Juan C. Almagro (ORCID: https://orcid.org/0000-0001-9420-1310)
- Gregorio Carballo‐Uicab (ORCID: https://orcid.org/0000-0002-9458-0776)
- Sandra Guerrero-Rodríguez
Institutions
- Tecnológico Nacional de México (MX)
- Instituto Politécnico Nacional (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-04
- DOI
- https://doi.org/10.3389/fimmu.2025.1531171
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94