A Case of McCune Albright Syndrome With Rare Extensive Polyostotic Fibrous Dysplasia
McCune-Albright syndrome is characterized by a triad of café au lait macules, polyostotic fibrous dysplasia (FD), and endocrine abnormalities. Bilateral and extensive presentation of FD is rarely reported. We report an interesting case of 24-year-old woman presenting with multiple episodes of slip and fall, sustaining multiple fractures with history of precocious puberty and skin complaints. On evaluation with 99m Tc-MDP bone scan, all the long bones, ribs, pelvic bones, frontal bone, and maxilla showed deformities and increased osteoblastic activity, suggesting extensive polyostotic FD. Thus emphasizing the crucial role of 99m Tc-MDP bone scan in the diagnosis of extensive FD and guides in understanding of the polyostotic involvement.
Authors
- Harish Goyal (ORCID: https://orcid.org/0000-0001-8849-5885)
- Harinee Ganesan
- Vasanth Madivanane
- Kabilash Dhayalane
- Ragire Sainath
Institutions
- Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1097/rlu.0000000000005674
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00