Comparative evaluation of root canal disinfection efficacy of three different endodontic irrigants using EndoVac: An in vitro bioluminescence-assisted study

G1 (7.90 ± 6.03) and G2 (2.90 ± 1.79) exhibited the least mean RLU values with no significant difference among them. It was noted that G5 (32.30 ± 7.92) performed better than G6 (14.20 ± 4.05) significantly (<i>P</i> < 0.008). G3 (27.70 ± 7.85) and G4 (28.50 ± 6.62) irrespective of irrigation protocols did not show significant differences in disinfection efficacy. Irrespective of irrigation protocol used, all the 3 irrigants exhibited a decrease in RLU values. In our study, EndoVac irrigation system did not improve the disinfection efficacy of the irrgiants.