Aerobic Exercise Training and Depressive Symptoms in People With Multiple Sclerosis: Brief Report on Default-Mode Network Resting-State Functional Connectivity
The overall pattern of results suggests that resting-state functional connectivity within the DMN may represent a potential neural mechanism underlying the beneficial effects of exercise on depressive symptoms in people with MS. Such results warrant future consideration in the design and conduct of future RCTs that aim to treat MS-related depression with aerobic exercise training in people with MS who have been prescreened for clinical depression.
Authors
- Glenn R. Wylie (ORCID: https://orcid.org/0000-0002-7061-6658)
- Olesya Iosipchuk (ORCID: https://orcid.org/0000-0002-4544-6298)
- Brian M. Sandroff (ORCID: https://orcid.org/0000-0002-2013-7632)
- Robert W. Motl (ORCID: https://orcid.org/0000-0003-0112-2803)
Institutions
- Rutgers, The State University of New Jersey (US)
- University of Illinois Urbana-Champaign (US)
- Kessler Foundation (US)
- University of Illinois Chicago (US)
- Center for Neurosciences (US)
- Rutgers New Jersey Medical School (US)
Publication Details
- Journal
- International Journal of MS Care
- Published
- 2025-02-03
- DOI
- https://doi.org/10.7224/1537-2073.2024-003
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94