Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering
This study identified peripheral blood transcriptome signatures that could lead to the identification of clinically relevant NMOSD disease activity biomarkers, and further highlights the pivotal role of interferon and IL-10 signaling in NMOSD.
Authors
- Daisuke Motooka (ORCID: https://orcid.org/0000-0002-4616-9608)
- Tatsusada Okuno (ORCID: https://orcid.org/0000-0002-1208-936X)
- Makoto Kinoshita (ORCID: https://orcid.org/0000-0001-7012-6782)
- Yoshiaki Yasumizu (ORCID: https://orcid.org/0000-0002-9872-4909)
- Naoyuki Shiraishi (ORCID: https://orcid.org/0000-0003-3444-7153)
- Keigo Kihara
- Hisashi Murata
- Hideki Mochizuki (ORCID: https://orcid.org/0000-0002-0874-7542)
- Tomohiro Yata
- Shohei Beppu
- Toru Koda
- R. Yamamura
- Naoshi Koizumi
- Yasuko Sugiyama
- Itsuki Sano
Institutions
- The University of Osaka (JP)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-03
- DOI
- https://doi.org/10.3389/fimmu.2025.1508977
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science
- Core Research for Evolutional Science and Technology