Insulin resistance and β-cell dysfunction in individuals with normal glucose tolerance but elevated 1-h post-load plasma glucose
A 1-h PG ≥ 8.6 mmol/L in individuals with NGT is associated with substantial β-cell dysfunction, highlight the value of incorporating 1-h PG measurement into diagnostic assessments for early detection of insulin secretion impairments across age groups.
Authors
- Youyuan Huang
- Yahui Mu
- Aimei Dong (ORCID: https://orcid.org/0000-0003-3743-7479)
- Qianwen Nie
- Xue Jin
Institutions
- Peking University (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-02-03
- DOI
- https://doi.org/10.3389/fendo.2025.1507107
- Citations
- 6
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 7.77
Funders
- Peking University
- Beijing Municipal Natural Science Foundation
- Fundamental Research Funds for the Central Universities