Rutaecarpine alleviates hepatic ischemia‒reperfusion injury in liver transplantation by inhibiting inflammatory response and oxidative stress
Rut alleviates hepatic IRI by targeting PDE4B to inhibit inflammation and oxidative stress. These findings highlight the potential of Rut as a drug candidate for the treatment of patients undergoing LT.
Authors
- Zhujun Yi
- Shengwei Li (ORCID: https://orcid.org/0000-0002-1647-1363)
- Yi Yan (ORCID: https://orcid.org/0000-0003-2860-3252)
- Xiang Li (ORCID: https://orcid.org/0000-0003-0724-0982)
- Feng Qi
Institutions
- Chongqing University (CN)
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Three Gorges University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-03
- DOI
- https://doi.org/10.3389/fphar.2025.1539744
- Citations
- 1
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.99
Funders
- Chongqing University