Transcriptomic analysis of Rhipicephalus microplus hemocytes from female ticks infected with Babesia bovis or Babesia bigemina
The differential gene expression of R. microplus hemocytes revealed that genes highly regulated upon Babesia infection were related to metabolism, tick immunity, cell growth, apoptosis, development, metabolism, and reproduction. Additional research is necessary to further define the genes that exhibited varying expression levels in hemocytes during the infection. The findings of this study will enhance our understanding on how Babesia parasites survive in the hostile environment of ticks and perpetuate their transmission cycle, ultimately contributing to the spread of bovine babesiosis.
Authors
- Rubikah Vimonish
- Naomi S. Taus (ORCID: https://orcid.org/0000-0001-5928-6232)
- Massaro W. Ueti (ORCID: https://orcid.org/0000-0002-2680-6091)
- Perot Saelao (ORCID: https://orcid.org/0000-0003-1171-9187)
- Janaína Capelli‐Peixoto (ORCID: https://orcid.org/0000-0001-8571-5870)
- Lowell S. Kappmeyer (ORCID: https://orcid.org/0000-0002-4081-4995)
- Chungwon Chung
- Wendell C. Johnson
Institutions
- Knipling-Bushland U.S. Livestock Insects Research Laboratory (US)
- Washington State University (US)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1186/s13071-025-06662-w
- Citations
- 4
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 8.19
Funders
- U.S. Department of Agriculture
- National Institute of Food and Agriculture
- Agricultural Research Service