Conventional type 1 dendritic cells in the lymph nodes aggravate neuroinflammation after spinal cord injury by promoting CD8+ T cell expansion
Migratory cDC1s and resident cDC1s promote the expansion of CD8<sup>+</sup> T cells in LNs around the injured spinal cord and mediate the adaptive immune response to aggravate neuroinflammation in SCI.
Authors
- Xiaoyi Wang (ORCID: https://orcid.org/0000-0001-7748-2296)
- Liqing Wang (ORCID: https://orcid.org/0000-0001-7308-9374)
- Hengjun Zhou (ORCID: https://orcid.org/0000-0002-3661-8959)
- Yuehui Ma (ORCID: https://orcid.org/0000-0002-9520-1248)
Institutions
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1186/s10020-024-01059-4
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- National Natural Science Foundation of China