Gallic acid protects intervertebral disc cells from ferroptosis and alleviates intervertebral disc degeneration by regulating key factors of oxidative stress
The alleviation of disc degeneration ferroptosis by GA may be closely associated with the key ferroptosis proteins P53 and NRF2.
Authors
- Boxue Zhang
- Yujiang Liu
- Zeling Huang (ORCID: https://orcid.org/0000-0002-2014-9844)
- Chaofeng Zhang (ORCID: https://orcid.org/0000-0002-1265-8681)
- Zaishi Zhu
- Xiaoqing Shi (ORCID: https://orcid.org/0000-0002-3675-7326)
- Yuwei Li (ORCID: https://orcid.org/0000-0003-1522-5643)
- Bo Xu (ORCID: https://orcid.org/0000-0002-8877-0610)
- Hua Chen (ORCID: https://orcid.org/0000-0002-4410-6742)
- Xiaofeng Shen (ORCID: https://orcid.org/0000-0002-6800-7044)
- Shuai Pei
- Lishi Jie (ORCID: https://orcid.org/0000-0003-4158-1844)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Suzhou Traditional Chinese Medicine Hospital (CN)
- Jiangsu Province Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-03
- DOI
- https://doi.org/10.3389/fphar.2025.1501725
- Citations
- 4
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 5.89
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- Nanjing University of Chinese Medicine
- Nanjing University