Gut-brain axis mediated by intestinal content microbiota was associated with Zhishi Daozhi decoction on constipation
Constipation induced by HFHPD and loperamide hydrochloride disrupts the structure of the intestinal microbiota. ZDD appears to alleviate constipation, potentially through mechanisms linked to the brain-gut axis and its interaction with the intestinal microbiota. Among the treatment groups, the medium dose of ZDD demonstrated the most effective results.
Authors
- Xinxin Peng (ORCID: https://orcid.org/0000-0002-1503-5404)
- Junxi Shen (ORCID: https://orcid.org/0000-0003-1653-4966)
- Na Deng (ORCID: https://orcid.org/0000-0002-4557-5372)
- Leyao Fang (ORCID: https://orcid.org/0000-0002-8226-2017)
- Xin Yi (ORCID: https://orcid.org/0000-0003-2988-1588)
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-02-03
- DOI
- https://doi.org/10.3389/fcimb.2025.1539277
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Hunan University
- Natural Science Foundation of Hunan Province
- Hunan University of Chinese Medicine