Multifactorial diseases in the genesis of perinatal pathology

A team of authors have conducted a study on the influence of multifactorial diseases of relatives of three generations of two lines of descent on the formation of perinatal pathology in children. To conduct the study, a special questionnaire was developed, consisting of 8 blocks, one of which allows to identify family perinatal problems. The analysis of the data obtained showed that an unfavorable perinatal period of parents increases the risk of having a child with perinatal pathology, and a family history of preterm birth increases the frequency of the birth of a premature child. The study revealed that the highest impact on the development of multifactorial diseases in adulthood is exerted by child health disorders in the perinatal period, such as prematurity, intrauterine hypoxia/asphyxia during childbirth, respiratory disorders and birth trauma. In turn, a multifactorial pathology in relatives, among which the most common are hypertension (18.7%), coronary heart disease (17.3%) and gastric ulcer (10.5%) with the burden increasing from generation to generation, serves as a risk factor for the birth of a child with perinatal pathology.

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Publication Details

Journal
Archives of Pediatrics and Pediatric Surgery
Published
2025-02-03
DOI
https://doi.org/10.31146/2949-4664-apps-2-3-4-9
Primary Topic
Neonatal Respiratory Health Research
Type
article
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article

Multifactorial diseases in the genesis of perinatal pathology

Tatyana Sokolovskaya, Н. Д. Одинаева, В.С. Ступак
Archives of Pediatrics and Pediatric Surgery
Neonatal Respiratory Health Research
article

Multifactorial diseases in the genesis of perinatal pathology

Tatyana Sokolovskaya, Н. Д. Одинаева, В.С. Ступак
article en

Abstract

A team of authors have conducted a study on the influence of multifactorial diseases of relatives of three generations of two lines of descent on the formation of perinatal pathology in children. To conduct the study, a special questionnaire was developed, consisting of 8 blocks, one of which allows to identify family perinatal problems. The analysis of the data obtained showed that an unfavorable perinatal period of parents increases the risk of having a child with perinatal pathology, and a family history of preterm birth increases the frequency of the birth of a premature child. The study revealed that the highest impact on the development of multifactorial diseases in adulthood is exerted by child health disorders in the perinatal period, such as prematurity, intrauterine hypoxia/asphyxia during childbirth, respiratory disorders and birth trauma. In turn, a multifactorial pathology in relatives, among which the most common are hypertension (18.7%), coronary heart disease (17.3%) and gastric ulcer (10.5%) with the burden increasing from generation to generation, serves as a risk factor for the birth of a child with perinatal pathology.

Archives of Pediatrics and Pediatric SurgeryVol. 2(3)
Federal Research Institute for Health Organization and Informatics (RU), Ministry of Health of the Russian Federation (RU)
Good health and well-being
Openalex Percentile: Top 97%
Neonatal Respiratory Health Research
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