Study on the Regulated Cell Death of Hypertrophic H9c2 Cells Induced by Au:Ag Nanoparticles
In conclusion, low doses of high-Ag load in Au:Ag NPs produced cytotoxicity on H9c2 cardiac cells, with hypertrophic cells being more susceptible. These results suggest that cardiac hypertrophic conditions are more prone to a cytotoxic response in the presence of bimetallic Au:Ag NPs compared to healthy cells. In addition, this work opens the door to explore the nanotoxicity of noble metal-based NPs in biological disease conditions.
Authors
- Omar Lozano (ORCID: https://orcid.org/0000-0003-3156-5779)
- Eduardo Vázquez‐Garza (ORCID: https://orcid.org/0000-0001-7149-8334)
- E. Campos‐González (ORCID: https://orcid.org/0000-0001-5215-6494)
- Jorge L. Cholula‐Díaz (ORCID: https://orcid.org/0000-0002-4457-1572)
- Helen Yarimet Lorenzo-Anota (ORCID: https://orcid.org/0000-0001-9560-4357)
- M. López (ORCID: https://orcid.org/0009-0002-5161-6908)
- Andrés Galindo-Padrón
- Mayte Rueda-Munguía
- Alejandra García-Carrasco
Institutions
- Instituto Nacional de Investigaciones Nucleares (MX)
- Tecnológico de Monterrey (MX)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/ijn.s491288
- Citations
- 5
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 3.99