Medical management of cerebellar mutism syndrome at a quaternary children’s hospital
We report the largest cohort of CMS patients treated with SSRIs. The lack of overall clinical benefit when compared to untreated patients in our study may be due to the length of delay in starting an SSRI, since early initiation of fluoxetine correlated with shorter CMS symptoms. These results support the importance of early clinical detection of CMS and potentially treating CMS early in the patient's postoperative course.
Authors
- Peter J. Madsen (ORCID: https://orcid.org/0000-0001-9266-3685)
- Emily Xu
- Kristen Park (ORCID: https://orcid.org/0000-0001-5527-3047)
- Phillip B. Storm (ORCID: https://orcid.org/0000-0002-7964-2449)
- Alexander M. Tucker
- Jonathan M. King (ORCID: https://orcid.org/0000-0003-1791-0636)
- Jimmy W. Huh (ORCID: https://orcid.org/0000-0003-4268-4829)
- Iris Paltin
- Mahaa Ayub
- Chao Zhao (ORCID: https://orcid.org/0000-0003-1739-1151)
- Emily Zhang (ORCID: https://orcid.org/0000-0002-9053-1336)
- Amish C Shah
- Shih-Shan Lang
Institutions
- Children's Hospital of Philadelphia (US)
- University of Pennsylvania (US)
- Philadelphia University (US)
Publication Details
- Journal
- Child s Nervous System
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1007/s00381-025-06759-8
- Primary Topic
- Fetal and Pediatric Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00