KLF12 Aggravates Angiotensin II‐Induced Cardiac Remodeling in Male Mice by Transcriptionally Inhibiting SMAD7
In conclusion, KLF12 promoted the development of angiotensin II-induced cardiac remodeling in male mice. Targeting KLF12 may be a promising therapeutic approach to treat cardiac remodeling.
Authors
- Min Hu (ORCID: https://orcid.org/0000-0002-7018-3872)
- Xiaofeng Zeng (ORCID: https://orcid.org/0000-0002-3883-2318)
- Qizhu Tang (ORCID: https://orcid.org/0000-0003-2210-3169)
- Shi‐Yu Huang (ORCID: https://orcid.org/0000-0002-3721-987X)
- Shasha Wang (ORCID: https://orcid.org/0000-0002-7750-7964)
- Yuxin Hu (ORCID: https://orcid.org/0009-0004-6386-9085)
- Teng Teng (ORCID: https://orcid.org/0000-0001-9481-8185)
- Ying Gao (ORCID: https://orcid.org/0000-0002-9786-5312)
Institutions
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1161/jaha.124.037455
- Citations
- 2
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Wuhan University
- Fundamental Research Funds for the Central Universities