Comparative Effectiveness of Rosuvastatin Versus Atorvastatin in Acute Ischemic Stroke Treatment
The results of this analysis of a large cohort of patients with ischemic stroke suggested that, compared with atorvastatin, rosuvastatin was significantly associated with a reduced risk of a 1-year composite of recurrent stroke, myocardial infarction, and all-cause mortality in patients with acute ischemic stroke. However, in real clinical practice, rosuvastatin is used less than one-fifth as frequently as atorvastatin in patients with acute ischemic stroke. This study serves as a hypothesis-generating function.
Authors
- Wook‐Joo Kim (ORCID: https://orcid.org/0000-0001-5290-0623)
- Kyung‐Ho Yu (ORCID: https://orcid.org/0000-0002-8997-5626)
- Jihoon Kang (ORCID: https://orcid.org/0000-0001-5715-6610)
- Jee‐Hyun Kwon (ORCID: https://orcid.org/0000-0002-5894-3146)
- Mi Sun Oh (ORCID: https://orcid.org/0000-0002-6741-0464)
- Wi‐Sun Ryu (ORCID: https://orcid.org/0000-0002-2823-5253)
- Tai Hwan Park (ORCID: https://orcid.org/0000-0002-5148-1663)
- Kwang‐Yeol Park (ORCID: https://orcid.org/0000-0003-4570-3538)
- Keun‐Sik Hong (ORCID: https://orcid.org/0000-0002-4684-6111)
- Ji Sung Lee (ORCID: https://orcid.org/0000-0001-8194-3462)
- Man‐Seok Park (ORCID: https://orcid.org/0000-0002-0637-5394)
- Soo Joo Lee (ORCID: https://orcid.org/0000-0001-8622-7000)
- Jeong‐Ho Hong (ORCID: https://orcid.org/0000-0002-8235-9855)
- Byung‐Chul Lee (ORCID: https://orcid.org/0000-0002-3885-981X)
- Sung‐Il Sohn (ORCID: https://orcid.org/0000-0002-6900-1242)
- Dong‐Eog Kim (ORCID: https://orcid.org/0000-0002-9339-6539)
- Jae‐Kwan Cha (ORCID: https://orcid.org/0000-0002-1049-5196)
- Dong‐Ick Shin (ORCID: https://orcid.org/0000-0001-5770-0268)
- Kyu Sun Yum (ORCID: https://orcid.org/0000-0001-9815-7652)
- Hee‐Joon Bae (ORCID: https://orcid.org/0000-0003-0051-1997)
- Jay Chol Choi (ORCID: https://orcid.org/0000-0002-3550-2196)
- Jeffrey L. Saver (ORCID: https://orcid.org/0000-0001-9141-2251)
- Hong‐Kyun Park (ORCID: https://orcid.org/0000-0002-8120-2469)
- Yong‐Jin Cho (ORCID: https://orcid.org/0000-0001-6965-0771)
- Jong‐Moo Park (ORCID: https://orcid.org/0000-0002-4199-3024)
- Kyusik Kang (ORCID: https://orcid.org/0000-0002-4021-4439)
- Keon‐Joo Lee (ORCID: https://orcid.org/0000-0002-6571-7091)
- Juneyoung Lee (ORCID: https://orcid.org/0000-0001-8073-9304)
- Hyunsoo Kim (ORCID: https://orcid.org/0000-0001-9340-8619)
- Jun Lee (ORCID: https://orcid.org/0000-0001-8643-0797)
- Beom Joon Kim (ORCID: https://orcid.org/0000-0002-2719-3012)
- Dae‐Hyun Kim (ORCID: https://orcid.org/0000-0001-9761-7792)
- Sang‐Hwa Lee (ORCID: https://orcid.org/0000-0002-0609-1551)
- Joon‐Tae Kim (ORCID: https://orcid.org/0000-0003-4028-8339)
- Kyungbok Lee (ORCID: https://orcid.org/0000-0003-2663-7483)
- Jae Guk Kim (ORCID: https://orcid.org/0000-0003-1418-0033)
Institutions
- Ulsan College (KR)
- Hallym University (KR)
- University of California, Los Angeles (US)
- Korea University (KR)
- Eulji University (KR)
- Korea University Medical Center (KR)
- Dong-A University Hospital (KR)
- Soonchunhyang University Hospital Seoul (KR)
- Asan Medical Center (KR)
- Seoul National University Bundang Hospital (KR)
- University of Ulsan (KR)
- Seoul Medical Center (KR)
- Chonnam National University Hospital (KR)
- Dongguk University Ilsan Hospital (KR)
- Inje University Ilsan Paik Hospital (KR)
- Keimyung University Dongsan Medical Center (KR)
- Ulsan University Hospital (KR)
- Yeungnam University Medical Center (KR)
- Chung-Ang University Hospital (KR)
- Hallym University Sacred Heart Hospital (KR)
- Chungbuk National University Hospital (KR)
- Hallym University Chuncheon Sacred Heart Hospital (KR)
- Jeju National University Hospital (KR)
- Keimyung University (KR)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1161/jaha.124.038080
- Citations
- 4
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 8.03
Funders
- Chonnam National University
- Korea National Institute of Health