Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan

Our study is the first to investigate the prevalence and level of O. volvulus infection among pregnant women in onchocerciasis-endemic areas in Africa. Our results showed a high infection rate of O. volvulus among pregnant women, which may pose a risk for adverse materno-foetal outcomes. Pregnant women in South Sudan are a reservoir for parasite transmission. A clinical trial evaluating the potential beneficial effect of treating O. volvulus infected pregnant women with IVM should be considered, as our preliminary results and the literature suggest that IVM intake might not affect the newborn.

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Publication Details

Journal
Journal of Epidemiology and Global Health
Published
2025-02-03
DOI
https://doi.org/10.1007/s44197-025-00357-2
Citations
2
Primary Topic
Parasitic Diseases Research and Treatment
Type
article
Field-Weighted Citation Impact
2.79

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article

Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan

Raphael Awah Abong, Chiara Trevisan, Yak Yak Bol, Amber Hadermann et al.
2 citations
Journal of Epidemiology and Global Health
Parasitic Diseases Research and Treatment
2.79
article

Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan

Raphael Awah Abong, Chiara Trevisan, Yak Yak Bol, Amber Hadermann, Robert Colebunders, Joseph Nelson Siewe Fodjo, Stephen Raimon Jada, Katja Polman
article en
2 citations

Abstract

Our study is the first to investigate the prevalence and level of O. volvulus infection among pregnant women in onchocerciasis-endemic areas in Africa. Our results showed a high infection rate of O. volvulus among pregnant women, which may pose a risk for adverse materno-foetal outcomes. Pregnant women in South Sudan are a reservoir for parasite transmission. A clinical trial evaluating the potential beneficial effect of treating O. volvulus infected pregnant women with IVM should be considered, as our preliminary results and the literature suggest that IVM intake might not affect the newborn.

Journal of Epidemiology and Global HealthVol. 15(1)
University of Buea (CM), University of Antwerp (BE), University of Juba (SS), Instituut voor Tropische Geneeskunde (BE)
Fonds Wetenschappelijk Onderzoek
Gender equality
Openalex Percentile: Top 13%
Parasitic Diseases Research and Treatment
2.79
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Pregnant Women, a Potential Reservoir for Onchocerca volvulus? A Cross Sectional Study in Maridi County, South Sudan — Raphael Awah Abong, Chiara Trevisan, et al. · Journal of Epidemiology and Global Health (2025) | TGRS Research Map | TGRS