Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity
This work demonstrates the potential of droplet microfluidics for therapeutic peptidase engineering, offering a robust and accessible method to optimize enzyme properties for clinical applications.
Authors
- Philip A. Romero (ORCID: https://orcid.org/0000-0002-2586-7263)
- Pete Heinzelman (ORCID: https://orcid.org/0000-0002-5588-3731)
- Evelyn F Okal
Institutions
- University of Wisconsin–Madison (US)
- Duke University (US)
Publication Details
- Journal
- Journal of Biological Engineering
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1186/s13036-025-00482-3
- Primary Topic
- Innovative Microfluidic and Catalytic Techniques Innovation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of General Medical Sciences