Link between bilaterality and type 2 inflammation in respiratory epithelial adenomatoid hamartomas: A two-center retrospective cohort study
Bilaterally originating REAH in the superior nasal septum and olfactory cleft demonstrates pronounced type 2 inflammatory characteristics, suggesting potential differences in pathogenesis compared to unilateral REAH. These findings underscore the need for further investigation into REAH pathophysiology and emphasize the importance of bilaterality in clinical assessment.
Authors
- Yong Gi Jung (ORCID: https://orcid.org/0000-0001-7456-849X)
- Sang Duk Hong (ORCID: https://orcid.org/0000-0003-3075-1035)
- Hyo Yeol Kim (ORCID: https://orcid.org/0000-0002-2162-3202)
- Gwanghui Ryu (ORCID: https://orcid.org/0000-0002-3251-399X)
- Kyung Won Kwon (ORCID: https://orcid.org/0000-0002-0633-8374)
- Yujin Heo (ORCID: https://orcid.org/0000-0001-9577-6802)
Institutions
- Samsung (South Korea) (KR)
- Samsung Medical Center (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1371/journal.pone.0318452
- Citations
- 2
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 3.70