GOOD SYNDROME PRESENTING WITH PROGRESSIVE MUSCLE WEAKNESS FOLLOWING THYMECTOMY

We present the case of a patient with Good syndrome who developed progressive muscle weakness following thymectomy. Muscle biopsy revealed criteria consistent with inclusion body myositis. Throughout her illness, she developed pure red cell aplasia, respiratory failure, and recurrent respiratory infections. She was treated with intravenous immunoglobulins, pyridostigmine, and cyclosporine A, achieving stability in her hematologic condition but without improvement in her myopathic symptoms. This case highlights the potential role of the thymus in the pathogenesis of autoimmune manifestations.