Abnormal neuronal activity in the subthalamic nucleus contributes to dysarthria in patients with Parkinson's disease
Our findings indicate the crucial role of the STN in consonant encoding and dysarthria at the single-unit level. Both SUA firing patterns in the STN and DDK performance can be modulated by DBS.
Authors
- Baotian Zhao (ORCID: https://orcid.org/0000-0003-0920-6825)
- Jianguo Zhang (ORCID: https://orcid.org/0000-0002-2751-8462)
- Yichen Xu (ORCID: https://orcid.org/0009-0006-5743-1591)
- Zixiao Yin (ORCID: https://orcid.org/0000-0001-7088-8031)
- Anchao Yang (ORCID: https://orcid.org/0000-0001-9179-5571)
- Yin Jiang
- Jan Hlavnička (ORCID: https://orcid.org/0000-0002-8510-5535)
- Yanming Zhu (ORCID: https://orcid.org/0000-0001-7355-4512)
- Diao Yu (ORCID: https://orcid.org/0000-0002-1497-7344)
Institutions
- Harvard University (US)
- Capital Medical University (CN)
- China-Japan Friendship Hospital (CN)
- Beijing Tian Tan Hospital (CN)
- Beijing Institute of Neurosurgery (CN)
- Beijing Friendship Hospital (CN)
- Czech Technical University in Prague (CZ)
Publication Details
- Journal
- Neurobiology of Disease
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1016/j.nbd.2025.106830
- Citations
- 1
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39