ZC3H15 suppression ameliorates bone cancer pain through inhibiting neuronal oxidative stress and microglial inflammation
Our results provide evidence that suppressing ZC3H15 can alleviate BCP by restricting neuronal oxidative stress and microglial activation, contributing to the improvement of nociceptive behaviors. Therefore, we concluded that ZC3H15 may be a potential target for the management of BCP.
Authors
- Liquan Huang (ORCID: https://orcid.org/0000-0003-3400-0685)
- Naibao Zhou
- Hao Li (ORCID: https://orcid.org/0000-0001-8502-2556)
- Baosheng Wang (ORCID: https://orcid.org/0000-0002-0934-1659)
- Tristan D. Yan (ORCID: https://orcid.org/0000-0002-7473-1522)
Institutions
- Shandong Tumor Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Neoplasia
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1016/j.neo.2025.101123
- Citations
- 3
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 4.18