Enhanced myofibroblast differentiation of eMSCs in intrauterine adhesions
In conclusion, we have demonstrated here that the scar tissues in IUA biopsy are characterized with enhanced differentiation of pro-fibrotic fibroblast and myofibroblast. The number of eMSCs is reduced in IUA tissues, and their myofibroblast differentiation capability is increased.
Authors
- Meiqi Li (ORCID: https://orcid.org/0000-0003-3586-176X)
- Mai C
- Jianyong Xu (ORCID: https://orcid.org/0000-0003-1910-4603)
- Lan Yao (ORCID: https://orcid.org/0000-0001-6560-5631)
- Yumeng Li (ORCID: https://orcid.org/0000-0002-1073-4257)
- Jun Song (ORCID: https://orcid.org/0009-0004-9563-4192)
- Jingting Zhang (ORCID: https://orcid.org/0000-0003-3378-2363)
- Tao Yuan (ORCID: https://orcid.org/0000-0003-1624-6251)
- Shaoquan Shi
Institutions
- Northeast Agricultural University (CN)
- Southern University of Science and Technology (CN)
- Shenzhen Zhongshan Urological Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1186/s13287-025-04183-y
- Citations
- 3
- Primary Topic
- Surgical Sutures and Adhesives
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province