Severe Thrombocytopenia in Pregnancy Secondary to Influenza A

Thrombocytopenia is a common finding in pregnancy, with the majority due to gestational thrombocytopenia. Gestational thrombocytopenia is an innocuous condition that rarely requires treatment. Immune thrombocytopenia accounts for only a minority of thrombocytopenia in pregnancy and can have serious implications, especially in the peripartum period, including restrictions on birth plans and complications such as postpartum haemorrhage and neonatal thrombocytopenia. We present a case of possible immune thrombocytopenia secondary to influenza A infection. The case involves a 19-year-old, gravida-2, para-1, who developed severe thrombocytopenia shortly after influenza A, with a nadir platelet count of 31 × 10<sup>9</sup>/L. The platelet count returned to normal levels after six days of oral prednisolone 25 mg. This case highlights the importance of a thorough workup to identify more serious conditions causing thrombocytopenia.

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Publication Details

Journal
Cureus
Published
2025-02-03
DOI
https://doi.org/10.7759/cureus.78449
Primary Topic
Platelet Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Severe Thrombocytopenia in Pregnancy Secondary to Influenza A

Lisa Prior, Dalia Adel Sabet, Lilantha Wedisinghe
Cureus
Platelet Disorders and Treatments
article

Severe Thrombocytopenia in Pregnancy Secondary to Influenza A

Lisa Prior, Dalia Adel Sabet, Lilantha Wedisinghe
article en

Abstract

Thrombocytopenia is a common finding in pregnancy, with the majority due to gestational thrombocytopenia. Gestational thrombocytopenia is an innocuous condition that rarely requires treatment. Immune thrombocytopenia accounts for only a minority of thrombocytopenia in pregnancy and can have serious implications, especially in the peripartum period, including restrictions on birth plans and complications such as postpartum haemorrhage and neonatal thrombocytopenia. We present a case of possible immune thrombocytopenia secondary to influenza A infection. The case involves a 19-year-old, gravida-2, para-1, who developed severe thrombocytopenia shortly after influenza A, with a nadir platelet count of 31 × 10<sup>9</sup>/L. The platelet count returned to normal levels after six days of oral prednisolone 25 mg. This case highlights the importance of a thorough workup to identify more serious conditions causing thrombocytopenia.

CureusVol. 17(2)
Griffith University (AU), Bond University (AU), Ipswich Hospital (AU)
Good health and well-being
Openalex Percentile: Top 97%
Platelet Disorders and Treatments
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Severe Thrombocytopenia in Pregnancy Secondary to Influenza A — Lisa Prior, Dalia Adel Sabet, et al. · Cureus (2025) | TGRS Research Map | TGRS