Predictive Factors for Failed Nonsurgical Management of Long Bone Metastasis and Myeloma

Radiograph measurements of cortical involvement were the most clinically relevant for determination of metastatic lesion fracture risk; however, predictors of local failure not addressed in Mirels' score should be considered in clinical decisions about prophylactic fixation. Surgery may be underperformed for histologies commonly considered to be "low risk" for local progression after radiation therapy.

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Publication Details

Journal
JAAOS Global Research and Reviews
Published
2025-02-01
DOI
https://doi.org/10.5435/jaaosglobal-d-24-00362
Primary Topic
Management of metastatic bone disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Predictive Factors for Failed Nonsurgical Management of Long Bone Metastasis and Myeloma

Yixuan Amy Pei, Barzin Behzad, Cara A. Cipriano, Bradley Griffith et al.
JAAOS Global Research and Reviews
Management of metastatic bone disease
article

Predictive Factors for Failed Nonsurgical Management of Long Bone Metastasis and Myeloma

Yixuan Amy Pei, Barzin Behzad, Cara A. Cipriano, Bradley Griffith, Jaret M. Karnuta, Joshua Jones, Kristy Weber, Lori Jia
article en

Abstract

Radiograph measurements of cortical involvement were the most clinically relevant for determination of metastatic lesion fracture risk; however, predictors of local failure not addressed in Mirels' score should be considered in clinical decisions about prophylactic fixation. Surgery may be underperformed for histologies commonly considered to be "low risk" for local progression after radiation therapy.

JAAOS Global Research and ReviewsVol. 9(2)
Pacific Engineering (United States) (US), University of Pennsylvania (US)
Good health and well-being
Openalex Percentile: Top 97%
Management of metastatic bone disease
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Predictive Factors for Failed Nonsurgical Management of Long Bone Metastasis and Myeloma — Yixuan Amy Pei, Barzin Behzad, et al. · JAAOS Global Research and Reviews (2025) | TGRS Research Map | TGRS