Nickel-Catalyzed and Tetrahydroxydiboron-Mediated Allylation of Aldehydes with Allyl Alcohols
The allylation of carbonyl compounds to form homoallylic alcohols represents one of the significant synthetic transformations. In this letter, we describe a new method for the allylation of aldehydes with allyl alcohols facilitated by nickel chloride and tetrahydroxydiboron. This approach offers a mild and straightforward procedure for the synthesis of homoallylic alcohols from aldehydes and ketones.
Authors
- Daofan Ma
- Guangwei Wang (ORCID: https://orcid.org/0000-0003-4466-9809)
- Wentao Zhao (ORCID: https://orcid.org/0000-0003-4787-5245)
- Yingfan Yang (ORCID: https://orcid.org/0009-0003-2212-8937)
- Siyi Zhong
Institutions
- Tianjin University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1021/acs.joc.4c02978
- Citations
- 1
- Primary Topic
- Organoboron and organosilicon chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Tianjin University