What Is the Prevalence and Fate of Myxoid Soft-Tissue Tumors With an Indeterminate Diagnosis Prior to Resection?

Indeterminate diagnosis before resection in myxoid tumors is relatively common, compared with prior reports in nonmyxoid neoplasms. Patients with indeterminate diagnosis before resection had two times higher rate of positive margins at resection surgery and markedly shorter local recurrence-free survival at 5 years compared with patients with malignant diagnosis known preoperatively. Diagnostic uncertainty at the time of resection is associated with worse oncologic outcomes in myxoid tumors.

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Journal
JAAOS Global Research and Reviews
Published
2025-02-01
DOI
https://doi.org/10.5435/jaaosglobal-d-24-00370
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

What Is the Prevalence and Fate of Myxoid Soft-Tissue Tumors With an Indeterminate Diagnosis Prior to Resection?

Herbert S. Schwartz, Hakmook Kang, Ginger E. Holt, James P. Norris et al.
JAAOS Global Research and Reviews
Sarcoma Diagnosis and Treatment
article

What Is the Prevalence and Fate of Myxoid Soft-Tissue Tumors With an Indeterminate Diagnosis Prior to Resection?

Herbert S. Schwartz, Hakmook Kang, Ginger E. Holt, James P. Norris, Jennifer L. Halpern, Joanna Shechtel, Cullen P. Moran, Julia C. Quirion, Stephen Chenard, Reena Singh, David S. Smith, Samuel Johnson, Andrew B. Rees, Nicholson S. Chadwick, Joshua M. Lawrenz, Carlos Prieto‐Granada, Katherine S. Hajdu, Ben L. Coiner
article en

Abstract

Indeterminate diagnosis before resection in myxoid tumors is relatively common, compared with prior reports in nonmyxoid neoplasms. Patients with indeterminate diagnosis before resection had two times higher rate of positive margins at resection surgery and markedly shorter local recurrence-free survival at 5 years compared with patients with malignant diagnosis known preoperatively. Diagnostic uncertainty at the time of resection is associated with worse oncologic outcomes in myxoid tumors.

JAAOS Global Research and ReviewsVol. 9(2)
Universidad de Granada (ES), University of Kang Ning (TW), Smith Family (AU), Vanderbilt University Medical Center (US)
Good health and well-being
Openalex Percentile: Top 97%
Sarcoma Diagnosis and Treatment
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