A randomized controlled clinical study to evaluate the efficacy of Nasya with Devadarvadi Ghrita in the management of Ardhavabhedaka

Background: Ardhavabhedaka is one among the Shirorogas explained by our Acharyas in which Shoola is experienced in Ardha Bhaga of the Shiras. Ardhavabhedaka can be scientifically correlated with Migraine due to its cardinal features of Half sided headache. Ardhavabhedaka if not treated it can cause Netra and Shotra Nasha, hence an early treatment is essential. Devadarvadi Ghrita Nasya is indicated in Ardhavabhedaka by Acharya Harita, therefore, this study was conducted to access its efficacy. Objective: To compare the efficacy of Devadarvadi ghrita Nasya and Shadbindu taila Nasya in the management of Ardhavabedaka. Methodology: In this single-blind study, 40 patients exhibiting classical features of Ardhavabhedaka, who met the inclusion criteria, were divided into two groups of 20 patients each for analysis. Group A was treated with Devadarvadi Ghrita Nasya, while Group B was treated with Shadbindu Taila Nasya for 7 days, followed by a follow-up assessment on the 14th day, after which statistical analysis was conducted. Result: Although there was no statistical significance observed, both the groups demonstrated clinical significance in reducing the frequency, duration, severity of headache and giddiness. Conclusion: Devadarvadi Ghrita Nasya showed better results than Shadbindu Taila in the management of Ardhavabhedaka.