Deletion of sphingosine 1-phosphate receptor 1 in myeloid cells reduces hepatic inflammatory macrophages and attenuates MASH
Deletion of S1P1 in myeloid cells is sufficient to attenuate intrahepatic accumulation of monocyte-derived macrophages and ameliorate murine MASH.
Authors
- Harmeet Malhi (ORCID: https://orcid.org/0000-0002-0882-4990)
- Debanjali Dasgupta (ORCID: https://orcid.org/0000-0001-8307-9719)
- Nanditha Venkatesan (ORCID: https://orcid.org/0000-0003-0974-1828)
- Yasuhiko Nakao (ORCID: https://orcid.org/0000-0002-9353-2780)
- Fanta Barrow (ORCID: https://orcid.org/0000-0002-6025-1210)
- Chieh‐Yu Liao
- Gopanandan Parthasarathy (ORCID: https://orcid.org/0000-0002-8847-1645)
- P. Vineeth Daniel (ORCID: https://orcid.org/0000-0002-2612-9043)
- Xavier S. Revelo (ORCID: https://orcid.org/0000-0002-2754-509X)
- Myeong Jun Song (ORCID: https://orcid.org/0000-0001-5244-0372)
- Tejasav S. Sehrawat (ORCID: https://orcid.org/0000-0001-7346-5683)
- Kevin D. Pavelko (ORCID: https://orcid.org/0000-0001-7555-1315)
- Guneet Sidhu (ORCID: https://orcid.org/0000-0001-6107-9689)
- Amy S. Mauer (ORCID: https://orcid.org/0000-0001-9508-7150)
Institutions
- University of Minnesota (US)
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1097/hc9.0000000000000613
- Citations
- 3
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 2.42