The Spectrum of Functional, Structural and Patient-Reported Outcomes in Intermediate Age-Related Macular Degeneration – A MACUSTAR Study Report
The findings from this broad and comprehensive spectrum of assessments of structure, function, and patient-reported outcomes in iAMD suggest that the disease spectrum is diverse and heterogeneous and that further efforts are necessary to fully understand and characterize iAMD in all its complexities. A further in-depth characterization will enable novel enrichment strategies for clinical trials in iAMD.
Authors
- Adnan Tufail (ORCID: https://orcid.org/0000-0001-6131-7640)
- Frank Gerhard Holz (ORCID: https://orcid.org/0000-0001-8019-9272)
- David Paul Crabb (ORCID: https://orcid.org/0000-0001-8754-3902)
- Hannah Dunbar
- Sérgio Leal (ORCID: https://orcid.org/0000-0001-7870-0478)
- Matthias Schmid (ORCID: https://orcid.org/0000-0002-0788-0317)
- Deborah Cosette
- S.E. Poor
- Marlene Saßmannshausen (ORCID: https://orcid.org/0000-0001-5265-4645)
- Charlotte Behning (ORCID: https://orcid.org/0000-0002-9310-3804)
- Alison M. Binns (ORCID: https://orcid.org/0000-0001-8621-498X)
- José Cunha‐Vaz (ORCID: https://orcid.org/0000-0002-0947-9850)
- Ulrich F. O. Luhmann (ORCID: https://orcid.org/0000-0002-1993-1951)
- Jan Henrik Terheyden (ORCID: https://orcid.org/0000-0002-0174-4066)
- Robert Patrick Finger (ORCID: https://orcid.org/0000-0003-4253-7597)
- Steffen Schmitz-Valckenberg (ORCID: https://orcid.org/0000-0003-3358-9942)
- Carel B. Hoyng (ORCID: https://orcid.org/0000-0002-1358-5963)
- N. Zakaria
- J. Batuca
- Cecília Martinho
- Klaus-Peter Moll
Institutions
- Roche (Switzerland) (CH)
- Moorfields Eye Hospital NHS Foundation Trust (GB)
- Radboud University Nijmegen (NL)
- Zimmer Biomet (Netherlands) (NL)
- City, University of London (GB)
- University of Utah (US)
- Heidelberg University (DE)
- University Hospital Bonn (DE)
- University Hospital Heidelberg (DE)
- Radboud University Medical Center (NL)
- Institut für Medizinische Biometrie, Informatik und Epidemiologie (DE)
- Carl Zeiss (United States) (US)
- Novartis (United States) (US)
- Bayer (Switzerland) (CH)
- Association for Innovation and Biomedical Research on Light and Image (PT)
- Moorfields Eye Hospital (GB)
- European Clinical Research Infrastructure Network (FR)
- University Medical Centre Mannheim (DE)
- University College London (GB)
Publication Details
- Journal
- Ophthalmologica
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1159/000543231
- Citations
- 3
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 4.08
Funders
- European Federation of Pharmaceutical Industries and Associations
- European Commission