Emergency Department Workflow Times of Intravenous Thrombolysis with Tenecteplase versus Alteplase in Acute Ischemic Stroke: A Prospective Cohort Study before and during the COVID-19 Pandemic
The adoption of TNK during COVID-19 pandemic did not result in a change in EDLOS, DTN, or DTG times when compared to ALT in this cohort. Safety and clinical outcomes were similar between groups. Probably a greater benefit could have been seen in a drip and ship thrombolysis setting. Further research is needed to assess the potential advantages of TNK in drip and ship scenarios of IVT.
Authors
- Gabriel Cavada (ORCID: https://orcid.org/0000-0002-3558-0266)
- Pablo M. Lavados (ORCID: https://orcid.org/0000-0002-9118-9093)
- Alejandro M. Brunser (ORCID: https://orcid.org/0000-0002-8376-9450)
- Verónica V. Olavarría (ORCID: https://orcid.org/0000-0003-4300-9921)
- Matías Guzmán
Institutions
- Universidad del Desarrollo (CL)
- Clínica Alemana (CL)
- Hospital Padre Hurtado (CL)
Publication Details
- Journal
- Cerebrovascular Diseases Extra
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1159/000543900
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- H. Lundbeck A/S
- Clínica Alemana de Santiago