Prophylactic Aspirin Dose and Preeclampsia

In this cohort study of 13 828 women, no difference was found in preeclampsia incidence or bleeding complications between those using 150 to 160 mg of aspirin vs 75 mg of aspirin during pregnancy for preeclampsia prevention. These findings suggest that either dose may be a reasonable choice when using aspirin to prevent preeclampsia. However, large randomized trials investigating aspirin dose in pregnancy are still needed.

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Publication Details

Journal
JAMA Network Open
Published
2025-02-03
DOI
https://doi.org/10.1001/jamanetworkopen.2024.57828
Citations
10
Primary Topic
Pregnancy and preeclampsia studies
Type
article
Field-Weighted Citation Impact
20.57
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article

Prophylactic Aspirin Dose and Preeclampsia

Anna‐Karin Wikström, Roxanne Hastie, Jóhanna Gunnarsdóttir, Lina Bergman et al.
10 citations
JAMA Network Open
Pregnancy and preeclampsia studies
20.57
article

Prophylactic Aspirin Dose and Preeclampsia

Anna‐Karin Wikström, Roxanne Hastie, Jóhanna Gunnarsdóttir, Lina Bergman, Stephen Tong, Susanne Hesselman, Ellen Kupka, Catherine Cluver
article en
10 citations

Abstract

In this cohort study of 13 828 women, no difference was found in preeclampsia incidence or bleeding complications between those using 150 to 160 mg of aspirin vs 75 mg of aspirin during pregnancy for preeclampsia prevention. These findings suggest that either dose may be a reasonable choice when using aspirin to prevent preeclampsia. However, large randomized trials investigating aspirin dose in pregnancy are still needed.

JAMA Network OpenVol. 8(2)
Uppsala University (SE), University of Iceland (IS), The University of Melbourne (AU), Stellenbosch University (ZA), Mercy Hospital for Women (AU), National University Hospital of Iceland (IS), Center for Clinical Research Dalarna (SE), University of Gothenburg (SE)
Good health and well-being
Openalex Percentile: Top 0%
Pregnancy and preeclampsia studies
20.57
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