Utilisation of an in vivo malaria model to provide functional proof for RhopH1/CLAG essentiality and conserved orthology with P. falciparum
This work provides valuable insight regarding the essentiality of the RhopH1 clag genes to the NPPs functionality and validates the continued investigation of the RhopH complex as a therapeutic target to treat malaria infections.
Authors
- Tania F. de Koning‐Ward (ORCID: https://orcid.org/0000-0001-5810-8063)
- Mrittika Chowdury
- Georgina Bramwell (ORCID: https://orcid.org/0000-0002-9883-4892)
- Natalie A. Counihan (ORCID: https://orcid.org/0000-0002-8973-3344)
- Mitchell L. Trickey
Institutions
- Deakin University (AU)
Publication Details
- Journal
- Journal of Biomedical Science
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1186/s12929-024-01105-7
- Citations
- 5
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 9.39
Funders
- National Health and Medical Research Council