Statin-induced necrotising myositis with heart failure: a lesson in cautious prescribing of common drugs

Statins are widely prescribed for both the primary and secondary prevention of cardiovascular diseases. However, muscle-related side effects, including weakness, pain and myopathy, are common side effects of statins, reported in up to 5% of users. Here, we present the case of a rare but severe complication of statin use, statin-induced necrotising myositis, which manifested as severe muscle weakness, heart failure and significant morbidity. There are no standardised treatment guidelines for statin-induced myositis. Here, the patient was managed with intravenous immunoglobulin and other immunosuppressants, leading to a favourable outcome when combined with a multidisciplinary approach with physiotherapy, occupational therapy and long-term rehabilitation. Although the patient did not recover full muscle power, he manages at home with the support of walking aids and family.