Effect of strip type denture adhesives on Candida species colonization in complete denture wearing patients

The present study was planned to evaluate the influence of strip of denture adhesive on oral microflora, mainly <i>Candida species</i> in the participants who were instructed to use Super Polygrip Comfort Seal Strips denture adhesive for 14 days of trial period. 24 completely edentulous patients treated with complete denture were randomly divided into following - Control and Test group (12 each group). Test group was prescribed a strip denture adhesive and instructed to use it for 14 days. Samples of saliva were collected from all participants (both control and test groups) on 0 day, 7th and 14th day. Collected samples were diluted with standard protocol and coated on culture media of Sabouraud dextrose agar and incubated for 48 hours at 37°C. The CFU/ml was analyzed from both groups. Collected data then analyzed statistically with Mann - Whitney U - Test where α kept at ≤ 5%. No significant statistical difference was found between the control and the test group after the testing duration of 14 days. Thus, results suggested that strip denture adhesive did not have any influence on the colonization of <i>Candida species</i> during 14 days of test period and it is safe for the use in complete denture wearing patients.