Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti-Inflammatory Properties by Suppressing MAPK/STATs Signaling Pathways and ROS Production
ASB has the potentiality to reduce the levels of proinflammatory mediators and cytokines, decrease ROS production, and also down-regulate the MAPK and STATs signaling pathways, thereby exerting an anti-inflammatory effect. This implies that ASB could potentially serve as a viable approach for addressing inflammatory conditions.
Authors
- Shanshan Guo (ORCID: https://orcid.org/0000-0002-3880-4149)
- Jie-Li Lv
- Huanhuan Wang (ORCID: https://orcid.org/0000-0002-8741-2897)
- Yuan Liu (ORCID: https://orcid.org/0000-0003-1420-0276)
- Laibin Zhang (ORCID: https://orcid.org/0000-0002-3296-319X)
Institutions
- Henan Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jir.s501313
- Citations
- 2
- Primary Topic
- Medicinal plant effects and applications
- Type
- article
- Field-Weighted Citation Impact
- 4.76