Multidisciplinary Approach Towards Managing Hepatocellular Carcinoma - Experience of a Single Hepatobiliary Center

Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. A multidisciplinary approach is crucial for optimal management. This study aimed to evaluate the outcomes of HCC patients managed by a multidisciplinary team at a single hepatobiliary center.Objective: To assess the demographics, clinical characteristics, treatment modalities, and survival outcomes of HCC patients managed with a multidisciplinary approach.Methods: A retrospective observational study was conducted on 212 HCC patients diagnosed and managed at a tertiary care hospital in Pakistan. Data on demographics, etiology, tumor characteristics, treatment received, and survival were collected and analyzed.Results: The majority of patients were male (80.7%) with a mean age of 55.96 years. Hepatitis C (66.5%) was the most common risk factor. Most patients presented with intermediate to advanced stage disease (BCLC B: 45%; BCLC C: 24.5%). Transarterial chemoembolization (TACE) was the most frequently used treatment (46.2%). The presence of portal vein thrombosis was significantly associated with mortality (p<0.001).Conclusion: A multidisciplinary approach is essential for the management of HCC. Early detection and timely intervention are crucial for improved survival.