Impact of Diabetes on Outcomes of Laparoscopic Cholecystectomy: A Prospective Study

OBJECTIVES This study aims to assess the impact of diabetes on laparoscopic cholecystectomy (LC) outcomes, as optimizing results for diabetic patients undergoing this common surgery presents unique clinical challenges. METHODOLOGY We comprehensively analyzed 258 participants, comparing 60 individuals with diabetes to 198 non-diabetic counterparts. Key variables, including age, gender, BMI, comorbidities, ASA grade, and CCI index, were assessed. Additionally, intraoperative and postoperative characteristics, ultrasound findings, and outcomes were analyzed. RESULTSDiabetic individuals exhibited advanced age, a higher BMI, and increased severity of illness based on their ASA grade and CCI index. Intraoperatively, diabetic individuals showed higher probabilities of empyema of the GB (23.3%), thick wall gallbladder (3.8%), mucocele (8.3%), gangrenous (10.8%), and other complications. The model explained variability in outcomes such as severe complications (6.6%), intraoperative hemorrhages (5%), conversion to open surgery (4.2%), and length of hospital stay (1.58±1.01 SD). Persistent pain 13 (5.03%), port site infection 30 (11.6%), intraabdominal abscess 5 (1.9%), bile duct injury 8 (3.1%), jaundice 8 (3.1%), and readmission to the hospital 4 (1.5%) were noted.CONCLUSIONDiabetic individuals undergoing laparoscopic cholecystectomy present distinct clinical features and higher probabilities of specific intraoperative and postoperative complications. The multivariate analysis provides insights into the variability of outcomes, emphasizing the importance of tailored approaches for diabetic patients in this surgical context.