Serum chitotriosidase-1 (CHIT1) as candidate biomarker for mitochondriopathies
Serum CHIT1 concentration is significantly elevated in mitochondriopathies compared to healthy controls and other NMD, identifying CHIT1 as potential complementary biomarker in mitochondriopathies.
Authors
- Leila Motlagh Scholle (ORCID: https://orcid.org/0000-0003-1363-4726)
- Steffen Naegel (ORCID: https://orcid.org/0000-0003-1727-9362)
- Alexander Mensch (ORCID: https://orcid.org/0000-0003-0089-4473)
- Tobias Mayer (ORCID: https://orcid.org/0000-0002-4935-4710)
- Gisela Stoltenburg‐Didinger (ORCID: https://orcid.org/0000-0002-2534-3064)
- Andreas Hahn (ORCID: https://orcid.org/0000-0002-5157-8369)
- Laurie Foerster
- Lorenzo Barba (ORCID: https://orcid.org/0000-0003-1328-3620)
- Ilka Schneider (ORCID: https://orcid.org/0000-0002-7109-2542)
- Alexander E. Volk (ORCID: https://orcid.org/0000-0001-8505-0143)
- Markus Otto (ORCID: https://orcid.org/0000-0003-4273-4267)
- Torsten Kraya (ORCID: https://orcid.org/0000-0002-6060-3810)
- David Strube
- Anna Katharina Koelsch
- Karl-Stefan Delank (ORCID: https://orcid.org/0000-0003-4691-3588)
Institutions
- Universität Hamburg (DE)
- Justus-Liebig-Universität Gießen (DE)
- Klinikum St. Georg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Alfried Krupp Hospital (DE)
- University Hospital in Halle (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1007/s00415-025-12916-5
- Primary Topic
- Studies on Chitinases and Chitosanases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Baden-Württemberg Stiftung
- Fondation Thierry Latran
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung