Predictors of Secukinumab Treatment Response and Continuation in Axial Spondyloarthritis: Results From the EuroSpA Research Collaboration Network
In this European real-world study of patients with axSpA initiating SEC, predictors of achieving LDA by ASDAS-CRP and BASDAI at 6 months and remaining on treatment at 12 months included both clinical, patient-reported, and lifestyle factors, underscoring the complex mechanisms of real-world drug effectiveness.
Authors
- Vappu Rantalaiho (ORCID: https://orcid.org/0000-0002-7470-3070)
- Stylianos Georgiadis (ORCID: https://orcid.org/0000-0003-3485-9457)
- Johan K. Wallman (ORCID: https://orcid.org/0000-0002-4915-2924)
- Adrian Ciurea (ORCID: https://orcid.org/0000-0002-7870-7132)
- Sara Nysom Christiansen (ORCID: https://orcid.org/0000-0002-5063-9932)
- Maria Helena Lourenço (ORCID: https://orcid.org/0000-0001-6796-0207)
- Jakub Závada (ORCID: https://orcid.org/0000-0002-9802-6545)
- Brigitte Michelsen (ORCID: https://orcid.org/0000-0003-0103-2840)
- Daniela Di Giuseppe (ORCID: https://orcid.org/0000-0003-3817-8288)
- Karin Laas
- Anne Gitte Loft (ORCID: https://orcid.org/0000-0001-6374-841X)
- Katja Perdan Pirkmajer (ORCID: https://orcid.org/0000-0001-7778-4016)
- Michael John Nissen (ORCID: https://orcid.org/0000-0002-6326-1764)
- Laura Kuusalo (ORCID: https://orcid.org/0000-0001-5238-8439)
- Lykke Midtbøll Ørnbjerg (ORCID: https://orcid.org/0000-0002-7832-6831)
- Gary J. Macfarlane (ORCID: https://orcid.org/0000-0003-2322-3314)
- Paweł Mielnik (ORCID: https://orcid.org/0000-0002-3894-5371)
- Ólafur Pálsson (ORCID: https://orcid.org/0000-0001-5295-2183)
- Björn Guðbjörnsson (ORCID: https://orcid.org/0000-0003-4631-6505)
- Isabel Castrejón (ORCID: https://orcid.org/0000-0003-1811-2417)
- Merete Lund Hetland (ORCID: https://orcid.org/0000-0003-4229-6818)
- Mikkel Østergaard (ORCID: https://orcid.org/0000-0003-3690-467X)
- Bente Glintborg (ORCID: https://orcid.org/0000-0002-8931-8482)
- Žiga Rotar (ORCID: https://orcid.org/0000-0002-9323-9189)
- Helena Santos (ORCID: https://orcid.org/0000-0003-1396-8988)
- Karel Pavelká (ORCID: https://orcid.org/0000-0003-1952-8422)
- Z. Faizy Ahmadzay
- Simon Horskjær Rasmussen (ORCID: https://orcid.org/0000-0001-6928-277X)
- Marion Pons (ORCID: https://orcid.org/0000-0001-6531-9846)
- Marleen van de Sande
- Irene van der Horst-Bruinsma
- Cătălin Codreanu (ORCID: https://orcid.org/0000-0001-6600-9946)
Institutions
- Universidad Complutense de Madrid (ES)
- Reykjavík University (IS)
- University of Copenhagen (DK)
- Radboud University Nijmegen (NL)
- University of Ljubljana (SI)
- University of Turku (FI)
- University of Iceland (IS)
- Tampere University (FI)
- Lund University (SE)
- University of Aberdeen (GB)
- Aarhus University (DK)
- Charles University (CZ)
- Ljubljana University Medical Centre (SI)
- Turku University Hospital (FI)
- Glostrup Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Radboud University Medical Center (NL)
- Karolinska Institutet (SE)
- Hospital General Universitario Gregorio Marañón (ES)
- Reade (NL)
- Institute of Rheumatology (CZ)
- East Tallinn Central Hospital (EE)
- University Hospital of Zurich (CH)
- Sociedade Portuguesa de Cardiologia (PT)
- University Hospital of Geneva (CH)
- National University Hospital of Iceland (IS)
- Amsterdam Neuroscience (NL)
- Nova Medical (United States) (US)
- Kanta-Hämeen Keskussairaala (FI)
- Institute for Rheumatic Diseases (Japan) (JP)
- Arthritis UK (GB)
- Diakonhjemmet Hospital (NO)
- Instituto Português de Malacologia (PT)
- Centro Hospitalar de Lisboa Ocidental (PT)
- Tampere University Hospital (FI)
- Tampere University (FI)
- Skåne University Hospital (SE)
- Amsterdam University Medical Centers (NL)
- Helse Førde (NO)
- Center for Rheumatology (US)
- Sørlandet Sykehus (NO)
- Institute of Infection and Immunity (CA)
- Universidade Nova de Lisboa (PT)
- University of Amsterdam (NL)
Publication Details
- Journal
- The Journal of Rheumatology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.3899/jrheum.2024-0920
- Citations
- 3
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.00