Elevated SAMD3 expression in T cells predicts improved survival in pancreatic ductal adenocarcinoma patients
SAMD3 is a biomarker of T cell function, with elevated expression in T cells predicting improved survival. These findings highlight the potential of precision immunotherapy approaches for treating PDAC.
Authors
- Ziteng Li (ORCID: https://orcid.org/0000-0001-9691-2589)
- Enliang Zhou (ORCID: https://orcid.org/0000-0002-2916-2885)
- Liyan Wu
- Lingyi Fu (ORCID: https://orcid.org/0000-0002-3519-3127)
- Bokang Cui (ORCID: https://orcid.org/0000-0003-0334-9761)
- Shuo Li (ORCID: https://orcid.org/0000-0002-3718-2034)
- Lang Tian (ORCID: https://orcid.org/0000-0001-8638-3038)
- Xinxin Zhou (ORCID: https://orcid.org/0000-0003-0183-6400)
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1007/s00262-025-03948-x
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province