Normative values for lung, bronchial sizes, and bronchus-artery ratios in chest CT scans: from infancy into young adulthood
Question What are the developmental trends of quantitative lung CT parameters in patients from childhood into young adulthood? Findings The ratio between bronchus and pulmonary artery dimensions demonstrates consistent values across age groups, indicating synchronized growth between bronchi and paired pulmonary arteries. Clinical relevance Our findings highlight the importance of standardized CT protocol and volume acquisition, and emphasize the need for ongoing collection of normal chest CT scans to refine the proposed reference values.
Authors
- Michael McCartin (ORCID: https://orcid.org/0000-0001-5321-2478)
- Eleni‐Rosalina Andrinopoulou (ORCID: https://orcid.org/0000-0002-5372-4163)
- Pim A. de Jong (ORCID: https://orcid.org/0000-0003-4840-6854)
- Yuxin Chen (ORCID: https://orcid.org/0000-0003-2549-0838)
- Anders Lindblad (ORCID: https://orcid.org/0000-0002-0287-1876)
- Silvia Bertolo
- Marleen de Bruijne (ORCID: https://orcid.org/0000-0002-6328-902X)
- Silvia Gärtner (ORCID: https://orcid.org/0000-0002-8190-5092)
- Pierluigi Ciet (ORCID: https://orcid.org/0000-0003-4017-8957)
- F. Vermeulen (ORCID: https://orcid.org/0000-0003-2303-2470)
- Francesco Fraioli (ORCID: https://orcid.org/0000-0003-0821-6327)
- Stephen M. Stick (ORCID: https://orcid.org/0000-0002-5386-8482)
- Giovanni Morana (ORCID: https://orcid.org/0000-0003-3144-2963)
- Alan S. Brody (ORCID: https://orcid.org/0000-0002-6661-7682)
- Robert J. Fleck (ORCID: https://orcid.org/0000-0002-3456-503X)
- L. Riera (ORCID: https://orcid.org/0000-0002-2397-943X)
- Lauren Akesson (ORCID: https://orcid.org/0000-0002-7439-612X)
- Pilar García‐Peña (ORCID: https://orcid.org/0000-0001-6055-4409)
- Edward Y. Lee
- K. De Boeck
- Christian P. Mol
- Qianting Lv (ORCID: https://orcid.org/0000-0003-1113-9481)
- Harm A.W.M. Tiddens (ORCID: https://orcid.org/0000-0001-5628-6667)
- Daan Caudri (ORCID: https://orcid.org/0000-0002-8191-8598)
- Matteo Paoletti (ORCID: https://orcid.org/0000-0002-1221-7747)
- Wieying Kuo (ORCID: https://orcid.org/0000-0001-8846-3517)
- Arlette E. Odink
- Jean‐Paul Charbonnier
Institutions
- University of Copenhagen (DK)
- Cincinnati Children's Hospital Medical Center (US)
- Boston Children's Hospital (US)
- Harvard University (US)
- University of Cagliari (IT)
- The Kids Research Institute Australia (AU)
- Princess Margaret Hospital for Children (AU)
- Erasmus MC (NL)
- University Medical Center Utrecht (NL)
- Vall d'Hebron Hospital Universitari (ES)
- Erasmus MC - Sophia Children’s Hospital (NL)
- Ca' Foncello Hospital (IT)
- University College London (GB)
- University of Cincinnati (US)
- University of Gothenburg (SE)
- Erasmus University Rotterdam (NL)
- University of Cincinnati Medical Center (US)
- KU Leuven (BE)
Publication Details
- Journal
- European Radiology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1007/s00330-025-11367-w
- Citations
- 7
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 10.63
Funders
- Cincinnati Children's Hospital Medical Center
- University of Cincinnati
- University College London
- Göteborgs Universitet
- College of Medicine, University of Cincinnati
- Erasmus Universitair Medisch Centrum Rotterdam