Autologous osteoperiosteal transplantation achieves comparable repair effect and superior interface integration to autologous osteochondral transplantation in porcine osteochondral defects
As a recently developed procedure for treating osteochondral defects, AOPT has shown promising repair effect and is being increasingly adopted in clinical practice. This study presents histological evidence of the progressive transformation of the periosteum graft into cartilage-like tissue and demonstrates its ability to integrate with the surrounding tissue.
Authors
- Anhong Wang (ORCID: https://orcid.org/0000-0001-5413-0490)
- Jiying Zhang (ORCID: https://orcid.org/0000-0002-4344-9794)
- Xin Fu (ORCID: https://orcid.org/0000-0002-6786-9259)
- Qinwei Guo (ORCID: https://orcid.org/0000-0003-3600-9544)
- Hongjie Huang (ORCID: https://orcid.org/0000-0001-5300-4652)
- En Deng
- Linxin Chen (ORCID: https://orcid.org/0000-0003-0394-7251)
- Weili Shi (ORCID: https://orcid.org/0009-0008-3056-0937)
- Shuai Yang (ORCID: https://orcid.org/0000-0002-1548-2028)
- Xiaoning Duan
- Yanbin Pi
- Linghui Dai
Institutions
- Peking University (CN)
- Peking University Third Hospital (CN)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Journal of Orthopaedic Translation
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.jot.2024.12.005
- Citations
- 5
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 8.34
Funders
- National Natural Science Foundation of China
- Peking University
- Peking University Third Hospital