Protocol publication rate and comparison between article, registry and protocol in RCTs
While publishing trial protocols may enhance transparency in peer-review process, the initial registered protocol alone appears sufficient for ensuring consistency in primary outcomes and sample sizes. Protocol publication does not seem to provide additional significant benefits in terms of outcome reporting.
Authors
- Matthieu Jabaudon (ORCID: https://orcid.org/0000-0002-8121-1680)
- Étienne Merlin (ORCID: https://orcid.org/0000-0001-6527-7893)
- Bruno Pereira (ORCID: https://orcid.org/0000-0003-3778-7161)
- Sylvain Mathieu (ORCID: https://orcid.org/0000-0003-2017-3227)
- Damien Bouvier (ORCID: https://orcid.org/0000-0002-2707-4320)
- Ludovic Samalin (ORCID: https://orcid.org/0000-0003-0740-4019)
- Johan Gagnière (ORCID: https://orcid.org/0000-0002-1820-3362)
- Guillaume Villatte (ORCID: https://orcid.org/0000-0002-4322-6304)
- Emmanuel Coudeyre (ORCID: https://orcid.org/0000-0001-5753-2890)
- Romain Guièze (ORCID: https://orcid.org/0000-0001-7563-580X)
- Catherine Laporte (ORCID: https://orcid.org/0000-0001-9890-489X)
- Fréderic Dutheil (ORCID: https://orcid.org/0000-0002-1468-6029)
- Jean‐Baptiste Bouillon‐Minois (ORCID: https://orcid.org/0000-0002-6556-4187)
- I. de Chazeron (ORCID: https://orcid.org/0000-0003-1195-8372)
- Florence Thomas
- Anthony Buisson (ORCID: https://orcid.org/0000-0002-6347-409X)
- Emmanuel Futier (ORCID: https://orcid.org/0000-0002-6454-271X)
- Xavier Moisset (ORCID: https://orcid.org/0000-0002-8799-0750)
- Farès Moustafa (ORCID: https://orcid.org/0000-0003-0949-1558)
- Romain Eschalier (ORCID: https://orcid.org/0000-0003-3183-7084)
- Laurent Renard Triché (ORCID: https://orcid.org/0000-0002-3971-9093)
- De Chazeron Ingrid
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Institut Pascal (FR)
- Université Clermont Auvergne (FR)
- Université Paris Cité (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Sorbonne Paris Cité (FR)
- University of Clermont Auvergne (FR)
- Sigma Clermont (FR)
- Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
- Institut de Chimie de Clermont-Ferrand (FR)
- Clermont Université (FR)
- Centre de Recherche Épidémiologie et Statistique (FR)
Publication Details
- Journal
- BMC Medical Research Methodology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1186/s12874-025-02471-y
- Citations
- 4
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 5.59