Comparison of airway pressure release ventilation (APRV) versus biphasic positive airway pressure (BIPAP) ventilation in COVID-19 associated ARDS using transpulmonary pressure monitoring
Despite higher tidal- volumes / airway-pressures in APRV vs. BIPAP, TPPendinspiratory was not increased. However, in APRV median TPPendexpiratory was negative indicating an elevated risk of occult atelectasis in APRV- mode in CARDS. Therefore, TPP- monitoring could be a useful tool for monitoring a safe application of APRV- mode in CARDS.
Authors
- Hendrik Drinhaus (ORCID: https://orcid.org/0000-0001-8435-2246)
- Fabian Dusse (ORCID: https://orcid.org/0000-0001-7762-6966)
- Sandra Emily Stoll (ORCID: https://orcid.org/0000-0002-4803-1362)
- Alexander Mathes (ORCID: https://orcid.org/0000-0002-0231-0681)
- Bernd W. Böttiger (ORCID: https://orcid.org/0000-0001-8000-8931)
- Tobias Leupold
Institutions
- Albert Einstein College of Medicine (US)
- Montefiore Medical Center (US)
- University of Cologne (DE)
- University Hospital Cologne (DE)
Publication Details
- Journal
- BMC Anesthesiology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1186/s12871-025-02904-7
- Citations
- 1
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Universitätsklinikum Köln